The Department of Hepatobiliary and Pancreatic Surgery, Tokyo, Japan, published in this month's issue of WJS an very interesting study comparing the mass forming cholangiocarcinoma vs the intrahepatic cholangiocarcinoma with periductal invasion.
Between January 1, 1998, and December 31, 2004, a total of 94 patients with ICC underwent macroscopic curative resection, and the macroscopic type of the tumors was assessed prospectively. Seventy four patients presented with the MF type. A multivariate analysis was conducted to identify the potential prognostic factors.
The results revealed two independent prognostic factors: presence/absence of intrahepatic metastasis and the macroscopic type of the tumor. The periductal invasion type were significantly associated with jaundice, bile duct invasion, portal vein invasion, lymph node
involvement, and positive surgical margin.
They concluded that identification of the macroscopic type of the tumor is useful for predicting survival after hepatectomy in patients with ICC. The MF plus PI type of ICC appears to have a more unfavorable prognosis, even after radical surgery, than the MF type of ICC.
involvement, and positive surgical margin.
They concluded that identification of the macroscopic type of the tumor is useful for predicting survival after hepatectomy in patients with ICC. The MF plus PI type of ICC appears to have a more unfavorable prognosis, even after radical surgery, than the MF type of ICC.
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