Identifying Donors at Risk for Perioperative Complications During LDLT

The University of Rochester and Pennsilvania published a retrospective study this month, regarding the risk factors involving living donor liver transplantation.

It is no secret that this surgery poses some problems. First, the surgery, a hepatectomy is performed on a completely healthy patient, and second, this patient is not benefitted from the procedure. This makes the procedure a technical and ethical challenge.

Recently, during the ESOT Congress, Dr. Rene Adam, from the Paul Brousse Hospital, and memeber of the European Liver Transplant Registry (ELTR), commented on the statistics regarding LDLT. He made special emphasis on the 5 donor deaths to date.

The publication presented an extensive study, and identified center volume as a minor risk, and patient age > 50 years as a major risk factor.

American Journal of Transplantation 2007; 7: 2344–2349

* If you want to read the article you can download it from the "BOX" widget, in the inferior right column.

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ESOT: Adult-To-Adult Living Donor Liver Transplantation Using Dual Grafts

Dr. Chih-Chi Wang from the Department of Surgery at Kaohsiung Hospital, Taiwan, presented at the ESOT Congress, Prague, their experience with dual grafts for living donor liver transplantation.

They presented a prospective study including 150 adult LDLT and 5 dual graft transplantations. According to their results, 2 recipients received 1 right lobe and 1 left lobe, and the other two received two left lobes.

They concluded that dual graft transplantation provides sufficient volume in the recipient without jeopardizing donor safety. They also added that it should be considered and performed by an experienced center when a single donor is rejected based on volumetry requirements.

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